Stem cell crosstalk

Since stem cell numbers used for regenerative purposes is low in vivo, therapeutic benefits may largely result from cellular interactions including paracrine signaling and direct cell-cell contacts. There is evidence that regenerated tissue is built rather from host tissues than from (trans-) differentiated stem cells, but the latter immensely boost the host tissue cell reactions. Oral hard and connective tissue-derived cells are suspected to react in a unique manner to the presence of stem cells. Thus, we focus on the mutual interplay and synergisms between stem cells and oral tissue cells. The vision is to understand and hence apply the tissue-specific reactions to regenerative therapy strategies.


Susanne was P.I. at G.E.R.N. until December 2019

Assoc. Prof. (PD) Susanne Proksch, M.D.

Department of Operative Dentistry and Periodontology Freiburg University Medical Center


Habilitation at the Albert-Ludwigs University Freiburg, Germany
Doctorate at the Technical University Dresden, Germany
Dental Medicine at Ludwigs-Maximilians University Munich, Germany


Université Paris Descartes, France