Micro-patterned cell populations as advanced pharmaceutical drugs
Micro-patterning cells through geometrically defined adhesion sites allows controlling morphogenesis, polarity, cellular mechanics, proliferation, migration, differentiation, stemness, cell–cell interactions, and collective cell behavior. Consequently, generating micro-patterned therapeutic cells is a promising idea that has not yet been realized and few if any steps have been undertaken in this direction. Prof. Rolauffs and his team aim to expedite the development of patterned cell populations using cell-instructive biomaterials for improved functional control as drug delivery systems in the context of cells as pharmaceutical products.
Meet the team
Professor Bernd Rolauffs, M.D.
Director of the G.E.R.N. Research Center
Section Head, Translational Medicine for Cell-Based Therapies
W3 Univ.-Professor in Tissue Replacement
Dept. of Orthopedics and Trauma Surgery, Freiburg University Medical Center
ACADEMIC DEGREES
Habilitation at the Eberhard Karls University of Tübingen
Doctor of Medicine, Medical Faculty of University of Münster, Germany
Postdoctoral
RESEARCH FELLOWSHIPS
Dept. of Biochemistry, Rush University, Chicago, USA
Massachusetts Institute of Technology, Center for Biomedical Engineering, Boston, USA
Orthopedic RESIDENCY
Tübingen University Medical Center and BG Trauma Center Tübingen, Germany
Münster University Medical Center, Germany
Sunderland Royal Hospital, UK