Micro-patterned cell populations as advanced pharmaceutical drugs

Micro-patterning cells through geometrically defined adhesion sites allows controlling morphogenesis, polarity, cellular mechanics, proliferation, migration, differentiation, stemness, cell–cell interactions, and collective cell behavior. Consequently, generating micro-patterned therapeutic cells is a promising idea that has not yet been realized and few if any steps have been undertaken in this direction. Prof. Rolauffs and his team aim to expedite the development of patterned cell populations using cell-instructive biomaterials for improved functional control as drug delivery systems in the context of cells as pharmaceutical products.

Meet the team

Professor Bernd Rolauffs, M.D.

Director of the G.E.R.N. Research Center

Section Head, Translational Medicine for Cell-Based Therapies

W3 Univ.-Professor in Tissue Replacement

Dept. of Orthopedics and Trauma Surgery, Freiburg University Medical Center


Habilitation at the Eberhard Karls University of Tübingen

Doctor of Medicine, Medical Faculty of University of Münster, Germany


Dept. of Biochemistry, Rush University, Chicago, USA

Massachusetts Institute of Technology, Center for Biomedical Engineering, Boston, USA

Orthopedic RESIDENCY

Tübingen University Medical Center and BG Trauma Center Tübingen, Germany

Münster University Medical Center, Germany

Sunderland Royal Hospital, UK